These results suggest that bioavailability of Ca from AACa and DL-Ca lactate are substantially equal in increasing plasma Ca levels, bone mineral density and mechanical strength in both vitamin D-replete and vitamin D-deficient rats. In contrast, the groups fed the same diets under vitamin D-deficient condition showed no significant recoveries in both plasma Ca metabolism and bone mineralization although Ca bioavailability of AACa appeared to be slightly better than that of DL-Ca lactate. Despite of the differences of contents and chemical forms of Ca in diets, all the groups showed prompt and complete recoveries in both Ca and vitamin D malnutritions under vitamin D-replete condition and there was no significant difference among all the groups in increases of body weight gains and plasma Ca levels, and in decreases of plasma PTH level and Alp activity. Furthermore, femoral Ca and phosphorus contents, mineral density and mechanical strength were also measured. During and after feeding, concentrations of Ca, phosphorus, parathyroid hormone (PTH), 25-hydroxyvitamin D 3 (25-OH-D 3), 1 α, 25-dihydroxyvitamin D 3 and alkaline phosphatase (Alp) activity in plasma were measured. Vitamin D-deficient rats were fed ad libitum a vitamin D-free diet containing 0.44 % Ca or 1.20 % Ca adjusted with either AACa or DL-Ca lactate with or without oral supplementation of physiological dose (10 IU/rat/day) of vitamin D 3 for 28 days. Plasma Ca metabolism, bone mineral density and vitamin D-deficient rats were measured and compared each other. ![]() ![]() ![]() Bioavailability of calcium (Ca) from oyster shell electrolysate (Active Absorbable Ca: AACa) and DL-Ca lactate in rats was investigated.
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